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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc2fa320d5be1ceccf0d80f8f2f007129d0d7acdf366fd89ed00c7f06020b263' 
  AND token = 'khEUf1vEp9SVMT6LdLikojtCGI39NBJnzwgtmuV+kKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}