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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff404d3c66128bc7d52700fdac21b8977d11f085f212456fce435c7db9eda1ea' 
  AND token = 'GR5euGMfTAdx6+Am2ZILxU5LfkSYvcwVFf9HFLoqMkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}