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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b22c7f085ed31f2950e65a07d40d25338fcbfc69635b07cb6c6e51a6e0a23ab' 
  AND token = 'R9SSAB1Xcv89AlDJts2B7/P+A8YVZcF97RekBQfvHRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}