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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4904812db11df768bcc4ac81b7534f15b6dd244e85a43ed6427601d610d3d94f' 
  AND token = 'vWQltAdXqDf5io4I9ZosfJn82OukffSDPp7gM/ZSZxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}