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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3fd0dc747df726581558af362c8049e891089354aa00c7133ca2fb8c9d0386f' 
  AND token = 'sw5yiBBMFGsngbdGDb1iwPt3Y7YMVq5WnhiQiFgDiII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}