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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818eaa7932ed0acb6506e0b4b75afbe50b542bf40705cf4d80a2d9efe04addb7' 
  AND token = 'QoJUwuSqnWipUxgD9mqhyNPwHC3yVBLIUhPZ+O5ssc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}