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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52a43ca4ef2c02a40c3e48565693032eca2dc8224a44a5e54aeb25f01af03a9' 
  AND token = 'PfvKmQAQ4EEV22AXQCc1tJZ/NwaSHAa/fI44/S/I2ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}