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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b4ef012009f487e7eccb11891116deea47658c6a2d5e77e77aaf13aefcf118' 
  AND token = 'Usg1zfEjVRUBOuK3r6TVdMN0j6Uuy5PIDstaW3PtUY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}