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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42ced02e0d7d5a67eb78a93d9bd344c7d92056bd8b512a1cef4a0932658faa8' 
  AND token = 'IXHcfuWI9C0KA3p0QpRpOlQ0mOldiqMfKqGt5I0Mi9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}