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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0da3b14dca94f1854519e140590116d3168787ef3f7e19176cb7f8c4e6f8b3' 
  AND token = 'U1fqQYCsI00MDVtayWqL3W/wVMkD7+wQUmS9MqyMxnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}