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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ba01f2278514f4b9622470fb3d680cbb90dafc70d435803beab5244687dfd4' 
  AND token = '2t9rWa6y5IKRGUURSCwmc1j+5r4A48XqM+YF0SCSoHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}