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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7a6bbecb1085b5ca214bdc6f6b651b5ac0b93e08756a35e6666e01a2503411' 
  AND token = 'qy7tbM8/T3Rf4bBNCH6AcTZdT2Apbfudgj41Szfgp9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}