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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7a21e838298bb9ce1edbc4c84b3b9300c475292b5822141abe37f36f6aab5a' 
  AND token = 'IiU+vcgk2hFF54Or+hPCC9eDu3q5F1wwPmBETLYSxIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}