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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de7eef66b28136a0bc6e196b4a9f638ab019dd9bc826ff823cdf4c67f3f9207' 
  AND token = 'HflNB6OfYbs0VTgX+7EeI9G/YemqI+fi8hqe7tBaEMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}