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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f343cc1d70bb7646a2606ea0afc1cd77a60375de5d5036983e972decab870d2c' 
  AND token = 'qsmQKCjOXXZygwZOUSA4o0WBFnHcbigTd+kE0GOdWqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}