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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08e09a52720e0d2cdb242fdcc3d5a0a77508ac35571698dbe9c11ae8eef79365' 
  AND token = 'KGW9EEPHps/kD/GCByTCEPkC/0Q4vTj8B+8j0nIi7gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}