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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd048f65f53a3a5940d2da1d173c5e0757e147a29129a46ba1624970875e51f89' 
  AND token = 'O+0QIA65XXSIxOKYOsKi+C5bLwg05ll86gCb2u9ONFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}