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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4adb53ec89f46e2ef55886af91668acc36f67275348fbceaabd409e8a67838' 
  AND token = 'Yhgw2Xvtvjhn+LtM/y2vyR7buhFO4rb+Lzj7tvrz6d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}