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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c53792c60bda9592ce06e25ae7fa74d2b17ea1c1a00628006e5f224f05683ba' 
  AND token = 'pvujeeU/p5h2kxli0JgESl8F1rpd94sVfVGvwfaXoxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}