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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6d7c13aba858be86de9ab93d94526df27255e425c5c4df51a2b5ecbea77f99' 
  AND token = 'qxnzC+a7e3iNQXcxACtlEgAu8+AKaIKN6SB8V61+oQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}