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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f226b7e9bf8527b74c868d77379e0f161575237e133c98d91a4b6a8c778f6db' 
  AND token = '8ra5K73DZSbwWKAbsJ5A0vhow2FFtcJVhrl3QTohHD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}