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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c64d422a70957d8e8a768e4b983fa6f6fe74d109d90838d5fc79ead0e5c0a450' 
  AND token = 'qDCaKnbXQImyQmddI/kOxUJ7PvKQZ/VnLFu0G64xGq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}