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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0456b3bcc23de3ccdd1e335c308517b22e8ebb91d16f9768f62f86e6c7f0eb4f' 
  AND token = 'KxcA7BvofkBTbvxyB3cRF/i1Xga8kTdUZgSoU0TZvtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}