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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '663e5f6c6cea373518569cf409892a65b2fc4bf1066e2ac36b800e434dfb49cc' 
  AND token = 'zoA4/d00QSW3H5a9NyiOEuAEUwsfzj6FZMPts381JQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}