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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2efa7e28043a7518037e4e2a38ed7114a8093f107a25e2793cc034c4403c907b' 
  AND token = 'cXGe5DcExr14JdwbWvVk/IIVcvBDruwaVlWniuz6P1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}