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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8cd567c6bb3dda94252a2cc1227520335fe9cdc3bc2f55a37bb6f2ce64954b' 
  AND token = 'VHrOqGJMC4QDcC+c7d0K+u1qH9ZZtKeU2tQCSXZh3EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}