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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53350cf3df257ab6542be78ab41b20c344756327655b0beb6a9ef0b52571f6e' 
  AND token = 'jAiopYOufIesVmhXLGLgBuM/jUITAHonjpc3kRKnKrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}