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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228211ee67899530097ea70a054427ed25f36a44ce61fed641fef97d2f85fb42' 
  AND token = 'Z9Ae1QN1+AZFynN5PhUsJWRt2MYvF+0EjClZkqe9HKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}