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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e63af7c7419bbe4471a908acf072dca228b6d8f36b49eaf88ddd91fa7fc315' 
  AND token = '+2dvUl/rt7Db3KbF/ollDhlFoet7wqhk77Ham+7rP28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}