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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd818d168000e27df6edc77ccd7b138d903e3f1a7c1755ce801a111aadcc792d' 
  AND token = 'bZEr1/au2EwpE/YdopFfFlcBMdrVEtxy/Fyogl8WDVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}