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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526510f8f13fda0a58ef40e6fcb8a8efa54ba32aa09b89c97f849eec0ce272c9' 
  AND token = 'PEoYR8c1TVTrGyyhWe/E2qrWbeLhwvaCuy+YNIIeDcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}