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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150c0bbfb228a8d6e720509d066d6d64832ac1b902c8cc0b918f662e8057bdf5' 
  AND token = '8Y1XGshKk4QPtRRBleBeDTpWW7LGij0+Rb5xwyq6tnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}