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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1adc15da9d60828745b1c4b6ddca17e27021eb8e975fc95e823198071b6387de' 
  AND token = 'rTC4pitXz7NtBG5ZDE4pif433OsqqLa9FhJvCpr1Sik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}