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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0da971223ab4935c47d177b5b241c6828551e02dc1baf3f613c6df1ec0bd5c7' 
  AND token = 'JpV1ZcDO4Aab8Uyb6D3bszaeO71KBMUeflHxSTF4EbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}