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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc28ddef2426bf0d6e45d632d4abe087937265353a1c3adfa05b4b18c1ee915' 
  AND token = 'I+0GpKwRoCGTAswVOInp0yd10ayAcvOXXMcGehJOrRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}