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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c880b13d1ed17a46ed215d687c8b67b8f4d2652b42c2e8d31b4be37f43eca5d1' 
  AND token = '5hDElmsyZBcyFv+NPL05oTXYaS82heSwpsrFXa4ojLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}