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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e358d70578a8ba5dae1987aa7b2abd02aafab7ce5f4ec16614c711727531db4' 
  AND token = 'Rgo4MabOoLhU6jMR1VAd+0TW6CynsjsU1qjhhhWQqlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}