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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8d0d1660f30d564013be2ac6529fc40c9e74e67e5f6dba0b3289c48f4b1558' 
  AND token = 'diCYmg9+Q0aEIACswcYaTfSShFitqBqInNOnH1XLrq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}