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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0429e84da1c495cfc78eff3fa000ede4d507067898db6e0b6fc6a8b0a67b4e6b' 
  AND token = '1TOtcMl8nQ/Nl+4lOt2ZC+mz5Uiv9iQvHQh3wxJVEyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}