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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e9298ead7111482e0ce8bae7411816d5bf3b84bb2baf2266d4f419f1434ddc' 
  AND token = 'B1rb/X8k1EZ495l9M93ctbPZ9QQYErR5KT+15JyyVDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}