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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4de6cc0e9b1bdeb4b6a9ce78f5423198db983b82353464d51edc3ea663bd47c' 
  AND token = '+1a+v9WUUlxvfocHu12KwvsUVKYUZ4uffTDHlpZMKZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}