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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea3684adf6377e555f4954267c4e4a3b077c73652eddf714c9778025a12556b1' 
  AND token = 'oEupRQex5ZuvfVWRV2llCzNLjVjK5tW9PP/U7yMymiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}