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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48ead5611d42f26228ced622351b1456dd09d98bce62936591a54dccb630e5b' 
  AND token = 'm3X9pcrLPLppVfH+hIozJclNa3L3p1Ot6ZZIwYMbFz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}