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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a7b2e20402723da0868e378b8ce182e587eaa3f8926176872930f43712dcf1' 
  AND token = 'mKHuTveBJ2Nf4QW8rbfORs5GUSl8MdAEhLR1qtizXBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}