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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '240be8a658def8fd3f50a601a7e565bc3535652bdc61a68c061a8316fc35a331' 
  AND token = 'VjXDJnl1zs2ZlAkXn6LoTIV3YePu9Ro7EJOuIcu+j4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}