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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d10b9c542ebd0da5f7b4e655049df2e2d82ee69ebad72a1df923b898e7cc99' 
  AND token = 'YEcRGPua3XQa1YudH0SJgCaA7XESK4fGBKu27FbEYEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}