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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe8abd7bcb93da3b8810ef465b4beb6e211295df3a39e3042fbf6ad08e4495b' 
  AND token = 'cZWZtW02ZPZWsUVqO1PsaC26u10EZbo3v1beqMzFEE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}