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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749fb7a06f6a36796c2a84e423e3f2d8c6d73232e3e88940b01dc73074537a0b' 
  AND token = '/vpvqqPKI8MHTREkJERm9C8LGBHt89RwGz1de8fpsiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}