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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d110139b3ba4a79968a005c12fcbfc99f5c09be3a529b119133f359465ab84' 
  AND token = '5KJgEOjPopc6gaF3N7oI+limoxeosQ/ER1ObOaFEGx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}