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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54cd7bcec6f6dfa13c3eaf6093545a8eea1dfb334ad8d3db8c87a2953a8ce473' 
  AND token = '+0ItTA1rBjfZ2hFs+6Vaw3CcqPUFBdo03ZnAsNazvhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}